Pompeo declared that Iran is set to face "strongest sanctions in history" and laid out an extensive laundry list of conditions the Iranian regime would need to satisfy - including ending support for all Middle East terror groups - to enter into a new deal with the U.S. Pompeo reiterated the Trump administration's position that Iran's behavior in the region must be combatted forcefully and collectively, in contrasts to the 2015 nuclear agreement, which dealt only with Iran's nuclear program.
Pompeo is defending President Donald Trump's decision to withdraw from the 2015 deal during a speech Monday at the conservative Heritage Foundation.
"After our sanctions come into full force, it will be battling to keep its economy alive", he added.
Pompeo did offer Iran a series of dramatic potential US concessions if it agrees to make "major changes".
Mr. Pompeo is also on record as threatening retaliation for any Iranian threat against Israel.
The address comes as Trump focuses on a related gambit with nuclear-armed North Korea.
"If you try to fold all those in to a giant negotiation, a new jumbo Iran negotiation, a new treaty - that's what seems to be envisaged - I don't see that being very easy to achieve, in anything like a reasonable timetable", Johnson said before Pompeo spoke. He said he did not have a timeline, but that the administration would send envoys around the world in coming weeks to explain the plan.
With regard to relations with neighboring Arab countries, the Iranian official said that Arab sattes in the region should reassess their approach towards Iran, and called for their help to stabilize the already volatile region.
He did not mention Russian Federation or China, which both signed the nuclear accord and are unlikely to back greater US sanctions on Iran, a clear weakness in any new crackdown on Iran.
European leaders have strongly condemned the United States move to abandon the nuclear deal - a pact also involving Britain, China, France, Russia and Germany - and reimpose sanctions, seeing it as undermining regional security and a direct attack on their economic interests.
Judging by Iranian military's recent statements, they could potentially wreak havoc in the Middle East, Afghanistan, and any other place where the United States and its allies have interests in. He says the USA would restore full diplomatic and commercial ties with Iran and allow it to access advanced technology.
Some of Europe's biggest firms who rushed to do business with Iran after the nuclear deal now find themselves forced to choose between investing there or trading with the US.
"We would of course have wished that an important and strong partner like the USA had remained in the Vienna accord", Peter Beyer, coordinator for trans-Atlantic relations in German Chancellor Angela Merkel's government, said in a ZDF television interview on Tuesday. Iran must also allow nuclear "unqualified access to all sites throughout the country".
"Who are you to decide for Iran and the world?"
Europeans say that Pompeo's speech does not leave much room for negotiating with Iran. Federica Mogherini, the EU's foreign policy chief, rejected the approach saying there was "no alternative" to the existing nuclear deal which the U.S. has reneged on.
Pompeo also demanded that Iran cease from a range of activities throughout the Middle East that have long drawn the ire of the USA and its allies.
It is increasingly clear that Trump's decision to withdraw the United States from the JCPOA and his escalating anti-Iranian rhetoric has given the hardliners in Iran the excuse they needed to discredit Rouhani's moderate government and pave the way for his possible removal from office.
Calling the accord as an "embarrassment" that was "defective at its core", he also warned of severe consequences if Iran resumes its nuclear programme. "Since the agreement was signed, Hezbollah has been armed by Iran, with Israel as the target", said the Secretary of State.
German insurer Allianz and engineering conglomerate Siemens were among the first European entities which announced their intention to scale back business in Iran.
In return, sanctions imposed by the UN, US and European Union that had crippled Iran's economy were lifted.