It was a left hook to the ribs that crumpled Linares at 2:08 of the 10th round.
He got back up towards the end of the 10-count but was badly hurt and the referee had seen enough as Lomachenko scored a huge comeback TKO.
Vasyl Lomachenko made history on Saturday night as he stopped Jorge Linares to claim the WBO lightweight title and claim a world championship in a third weight division.
"That right hand, it was a great punch". Lomachenko was ahead 86-84 on judge Steve Weisfeld's scorecard, while Linares was up by the same score on Robin Taylor's card, and Julie Lederman had the fight even.
Barrera needed a knockout in the final round to win, and he was the more active fighter and landed more shots in the final round, but that knockout never came.
To hear the ESPN team call it - the house fighter was Loma, fighting for Top Rank on "Top Rank on ESPN" - Linares wasn't even in the ring (this writer had him in a year-end pound-for-pound top 10). "I've been busy and active so I feel like I'm very risky right now".
"All this talk that I want to fight him but my promoter doesn't want to allow me, that's a fighter hiding", Golden Boy's Robert Diaz said. But hard work and dedication got me back in there.
Linares will have been familiar to British fans having beaten Anthony Crolla twice past year, but Lomachenko's stock is rapidly rising in the professional ranks and this was a whole different kettle of fish for the Venezuelan.
Lomachenko weighed in at 134½ pounds Friday for his lightweight debut. However, Linares will - in my opinion - be capable of making Lomachenko think a lot more than any of his former professional opponents. He said at the post-fight news conference that he injured a hand in the second, but it was hardly noticeable in his performance. "My fans always pack the arena every time I fight here". By this time, the speed that Lomachenko possessed was very evident.
In the sixth round was something the fans Lomachenko did not expect.
Gonzalez warned Linares for a debatable low blow about 40 seconds into the sixth round.
Lomachenko did just that, and he has continued to break down his opponents both mentally and physically.
Linares did catch Loma with a sweet left uppercut with a minute remaining, but the two-time Olympian again made him pay with a stinging combo to the body. Linares recognized he likely had to press the attack and opened up a little more in the late rounds. The Venezuelan veteran landed the right hand on the button. "Now, he's moving up to 135, and people say, 'Is this a bridge too far?'" And his father , who is a great trainer says, 'No this isn't a bridge too far.' And we're going to see on Saturday.
Lomachenko ended the fifth with another flurry and his manager, Egis Klimas, stood in the corner smiling and nodding his head, knowing he has someone special.