Researchers say it could be preventable by making a few simple changes in your daily routine.
Smoking remains the biggest lifestyle cause of cancer, responsible for 54,000 cases - 15.1 per cent - annually, but the toll is falling as more people kick the habit.
This amounted to 7.5% of female cancer cases and 5.2% of male cancer cases.
More than 3,500 cases of cancer a year in Northern Ireland could be prevented through simple lifestyle changes.
Obesity only trails smoking as the main preventable cause of cancer in the UK.
Linda Bauld, Cancer Research UK's cancer prevention expert, told The Times: 'As a charity we have a responsibility to communicate evidence about risk.
Exposure to substances such as asbestos and UV radiation in the workplace each caused nearly 4% of cancer cases, while air pollution, consumption of processed meat and not breastfeeding each accounted for less than 2% of cancer cases.
It has now called for a ban on junk food adverts before the 9pm watershed.
"This research clearly demonstrates the impact of smoking and obesity on cancer risk".
"As part of its expected diet and obesity strategy, the Scottish government must tackle what is the biggest preventable health crisis of our generation and make a real difference to the future of everyone in Scotland". Most of these cases are linked to Human Papillomavirus (HPV) and H. Pylori.
The three leading causes of cancer account for at least 135,000 diagnoses in Britain every year which the CRUK says can be avoided.
"These figures show that we each can take positive steps to help reduce our individual risk of the disease", said Harpal Kumar, chief executive at the Cancer Research UK.
The research team says the new United Kingdom cancer rates have increased by 7% over the past decade which could be increased by about 2% every year.
"We have already reached a record low in the numbers of teenagers smoking, and halved the number of children being exposed to second hand smoke".