He was dropped for Saturday's defeat at Chelsea however, after rumours surfaced that manager Mauricio Pellegrino was unsure of some of his player's commitment to the cause, fuelling speculation that Van Dijk may finally be heading for the exit door.
Van Dijk had started 11 successive games before the trip to Stamford Bridge and the timing of his omission will only increase talk of a potential January move away from Southampton.
Pellegrino has now admitted that Van Dijk's future at the club is uncertain by saying, "I can't control the market, I am not the owner. I understand this but their behaviour has to be committed 100 per cent".
The Saints were left furious with Liverpool and their pursuit, and sources close to Southampton made it clear that the last thing they wanted to do was to allow the player to move to Anfield.
Liverpool and Manchester City have been handed a boost ahead of the January transfer window, with the news that Virgil van Dijk will not be kept at Southampton if the club feel he is not willing to give 100%.
"Vincent is always injured, he fights a lot to be ready but sometimes he is not able to be fit consistently and we have just three central defenders in that moment for competition".
He said: 'I can't control the market, I'm not the owner of the player.
Reds owners Fenway Sports Group subsequently assured Southampton that they would not make any further approach for the player unless they were invited to do so by the south coast club, but recent reports have suggested that the Merseyside club will launch a fresh attempt to sign the defender in January. After the board can decide altogether which is the best for the team.
I will recommend to try to keep our best player here at the club.