"Across the country, and in Maryland, this Thanksgiving weekend is expected to be the busiest for the holiday in more than 10 years", said AAA Mid-Atlantic spokeswoman Ragina Cooper Averella in a statement.
Experts say that is an increase of about 3.2 percent over a year ago.
This year is expected to see the most Thanksgiving travelers since 2005.
This would despite the fact that gas prices are the highest since Thanksgiving 2014.
Higher gas prices won't stop Floridians from hitting the road this Thanksgiving.
The company also added that according to AAA's Leisure Travel Index, travelers taking to the skies will pay the lowest average in five years for a round-trip flight for the top 40 domestic routes.
Gas prices jumped more than 10 percent after hurricanes Harvey and Irma, peaking on September 8 at an average of $2.67 a gallon.
"Most people have already made their travel plans, and will not cancel them for moderate shifts in gas prices", Jenkins said.
In Massachusetts, more than 1.1 million people expect to travel over Thanksgiving, and more than 975,000 of them will go by vehicle, AAA said. The numbers have been increasing every year since.
The AAA poll says a strong economy and high consumer confidence are contributing to the desire to travel, or at least provide the finances.
"Idaho has experienced a seasonal price drop, but it's been slower than in recent years", Conde said. "These factors are fueling a confident consumer, who is expected to maintain a high level of spending that should drive an increase in holiday travel".
Air travel is expected to see the biggest year-over-year increase, at 5 per cent, with about 4 million travellers expected to pass through U.S. airports over the holiday period. Nationally, Anaheim, site of the Disneyland Resort, is expected to be the second most popular Thanksgiving destination, according to the AAA.