Former Tottenham midfielder and manager Tim Sherwood says that his former club are "on the brink" of winning a trophy.
Despite the Arsenal manager's non-committal response, Lacazette seems nearly certain to regain his starting place after Wenger confirmed Olivier Giroud was likely to miss the match with the injury he picked up on worldwide duty last week. For what seems like the first time in decades, Tottenham is widely regarded as a clear favorite even though the match is taking place at Arsenal's Emirates Stadium.
It's the first match back after the global break for most of the Arsenal players but Arsebe Wenger was asked why Laurent Koscielny and Olivier Giroud were sent back early from the France squad.
Although, Arsenal manager Arsene Wenger is insistent that his side are not "underdogs" going into this weekend's clash. They now sit third in the Premier League and are through to the last-16 of the Champions League.
"Not at all. I think Tottenham is a good side but we have the quality to win this game and that is what we want to show", he told reporters.
The 26-year-old made something of a mockery of Wenger's decision by scoring just nine minutes after his second half introduction to briefly bring his side back into a contest which was eventually settled when Gabriel Jesus put City 3-1 ahead with a contentious goal.
Arsene Wenger has confirmed Arsenal will be looking to stop Harry Kane in particular on Saturday.
He added, "Two years ago when we finished above them we were disappointed because we didn't win the title".
But third-placed Tottenham, who have already beaten Real Madrid this season, will go in to the game full of confidence.
"We still have some people coming in today".
Harry Kane, Dele Alli and Harry Winks all withdrew from the England squad with injuries while Hugo Lloris and Toby Alderweireld were also missing for France and Belgium respectively.
Kane has scored in his last five games against Arsenal.