United sit joint top of the League table alongside bitter rivals, Manchester City with Mourinho knowing that City would most likely get a win at home to Stoke, victory is needed in Merseyside to keep pace with the leaders.
Belgium have already secured their place in Russian Federation next summer after finishing top in Group H and Martinez may opt to rest his first-choice striker against Cyprus.
There is an uncertainity surrounding Michael Carrick too which means the club will be with only Ander Hererra and Nemanja Matic in midfield. I haven't received a phone call from Jose Mourinho as yet'.
Belgium boss Roberto Martinez has declared Lukaku "100 per cent fit" in a tonic for United manager Jose Mourinho who is already without midfielders Paul Pogba and Marouane Fellaini for the Anfield tussle.
The Premier League returns on Saturday with an absolutely epic match.
Manchester United midfielder Marouane Fellaini is set to miss their Premier League clash against Liverpool after picking up a knee injury playing for Belgium.
Club legend Andrew Cole was also at the training ground on Tuesday, working out in the gym as he builds his strength following the kidney transplant he had earlier this year.